Anti-Cyclin E1 Antibody (3123)

Anti-Cyclin E1 Antibody (3123)

Product No.: 3123

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Target
Cyclin E1
Product Type
Polyclonal
Isotype
Rabbit
Applications
ELISA

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Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
Peptide corresponding to amino acids 43-52 of cyclin E1.
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4 with 0.02% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1:500-1:1,000.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Polyclonal Antibody specific to human cyclin E1, a protein (approx. 50 kD) expressed in elevated levels in human tumor cells. Cyclin E1 controls the initiation of DNA synthesis by activating cdk2, and i expression of cyclin E1 is upregulated by the E7 oncoprotein.

Antigen Details

Function
Essential for the control of the cell cycle at the G1/S (start) transition. {PubMed:7739542}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Indirect Elisa Protocol
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.