Anti-GLUT10 Antibody (28103)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen Synthetic peptide corresponding to amino acids 367-385 (ILSTAKKTKPHPRSGDPSA) of human GLUT10 conjugated to KLH at the N- terminus. Product Concentration Lot Specific Formulation PBS, pH 7.4. State of Matter Liquid Product Preparation Purified by peptide immuno-affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500 dilution. A band of approximately 57 kDa is detected.
Positive control: transfected cell lysate Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Polyclonal Antibody specific to GLUT10 Background Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetic causes. Genome-wide screening has identified several susceptibility loci for NIDDM within the human genome. Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUT or SLC2A family). The gene for GLUT10, localized to human chromosome 20q12-q13.1, is a candidate gene for NIDDM susceptibility. It is widely expressed, with highest levels in liver and pancreas. Function Facilitative glucose transporter required for the development of the cardiovascular system. {PubMed:11592815, PubMed:16550171}. NCBI Gene Bank ID UniProt.org Research Area Neuroscience References & CitationsWood,IS, Hunter,L and Trayhurn,P (2003) Biochem Biophys Res Commun 308: 43-49. McVie-Wylie,AJ, Lamson,DR and Chen,YT (2001) Genomics 72: 113-117. Technical Protocols Certificate of Analysis |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
