Antibody Details
Product Details
ImmunogenPurified Recombinant Human HCG (>98%)
FormulationThis purified antibody is supplied in 0.05 M phosphate buffered saline (PBS), pH 7.2 - 7.4, containing 0.1% sodium azide. as a preservative.
Storage and HandlingThis Purified Antibody is stable when stored at 2-8°C. Do not freeze.
Cross ReactivityhCG Test
Paired with Leinco Prod. No. C103 Clone No. 152: ihCG 111%, BhCG 100%, LH < 3%, FSH < 1%,
TSH < 1%.
LH Test
Paired with Leinco Prod. No. L100 Clone No. 196: LH 100%, BhCG < 1%, FSH < 1%, ihCG 78%,
TSH < 1%.
Paired with Leinco Prod. No. L101 Clone No. 199: LH 100%, BhCG < 1%, FSH < 1%, ihCG 3%,
TSH < 1%.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Description
Description
SpecificityMouse Anti-Human Chorionic Gonadotropin (HCG) (Clone 150) recognizes Human Chorionic Gonadotropin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
BackgroundHuman chorionic gonadotropin (hCG) is a glycoprotein hormone produced in pregnancy that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions; for instance, it is thought that hCG affects the immune tolerance of the pregnancy. Early pregnancy testing, in general, is based on the detection or measurement of hCG. Because hCG is produced also by some kinds of tumor, hCG is an important tumor marker, but it is not known whether this production is a contributing cause or an effect of tumorigenesis.
References & Citations
1. (2007 Feb. 23) Int. J. Gynaecol. Obstet.
2. (2007 Feb. 15) Fertil. Steril.
3. (2007 Feb. 9) Fertil. Steril.
4. (2007 Feb. 9) Fertil. Steril.
5. (2006 Mar.) Taiwan J. Obstet. Gynecol. 45(1):48
6. (2007 Jan. 26) Fertil. Steril.