Anti-Human Chorionic Gonadotropin Intact Purified

Anti-Human Chorionic Gonadotropin Intact Purified

Product No.: C101

[product_table name="All Top" skus="C101"]

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Clone
150
Target
Chorionic Gonadotropin Intact
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
CGB, CGB3, hCGB, MGC119822
Isotype
IgG

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human HCG (>98%)
Product Concentration
1.0 mg/ml
Formulation
This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide.
Storage and Handling
For long term storage freeze working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Cross Reactivity
hCG Test Paired with Leinco Prod. No. C103 Clone No. 152: ihCG 111%, BhCG 100%, LH < 3%, FSH < 1%, TSH < 1%. LH Test Paired with Leinco Prod. No. L100 Clone No. 196: LH 100%, BhCG < 1%, FSH < 1%, ihCG 78%, TSH < 1%. Paired with Leinco Prod. No. L101 Clone No. 199: LH 100%, BhCG < 1%, FSH < 1%, ihCG 3%, TSH < 1%.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Mouse Anti-Human Chorionic Gonadotropin (HCG) (Clone 150) recognizes Human Chorionic Gonadotropin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced in pregnancy that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions; for instance, it is thought that hCG affects the immune tolerance of the pregnancy. Early pregnancy testing, in general, is based on the detection or measurement of hCG. Because hCG is produced also by some kinds of tumor, hCG is an important tumor marker, but it is not known whether this production is a contributing cause or an effect of tumorigenesis.

References & Citations

1. (2007 Feb. 23) Int. J. Gynaecol. Obstet. 2. (2007 Feb. 15) Fertil. Steril. 3. (2007 Feb. 9) Fertil. Steril. 4. (2007 Feb. 9) Fertil. Steril. 5. (2006 Mar.) Taiwan J. Obstet. Gynecol. 45(1):48 6. (2007 Jan. 26) Fertil. Steril.

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.