Anti-COM1/p8 (NT) Antibody
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Peptide corresponding to the N-terminus of human p8 protein. Product Concentration Lot Specific Formulation Phosphate-buffered saline (PBS), pH 7.4, containing 0.02% sodium azide State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 8 kD is detected. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to p8 (NT) Background The human p8 gene encodes a nuclear protein with potent mitogenic properties, promoting enhanced cell proliferation. Its expression is notably induced in the pancreas during episodes of acute pancreatitis, suggesting a role in stress response and tissue regeneration. While p8 expression does not alter cellular responses to TNF-α or staurosporine-induced apoptosis, cells expressing p8 exhibit significantly increased growth rates, highlighting its potential involvement in cell cycle regulation and recovery from injury. Antigen DetailsNCBI Gene Bank ID UniProt.org Research Area Growth Factors, Cytokines, Receptors References & CitationsTechnical Protocols |
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