Bee Venom Phospholipase A2 (13824P)
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Antibody DetailsProduct DetailsReactive Species Bee Product Concentration Lot Specific Formulation Solution in 20mM Tris-HCl, pH 7.2, 1.5M urea, and 50% glycerol. State of Matter Liquid Storage and Handling Stable for at least one (1) year if stored below -20°C. Avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Recombinant Bee Venom Phospholipase A2 Background Bee venom phospholipase A2 (BV-PLA2) is the primary allergen in bee venom. It is a hydrolytic enzyme which cleaves the sn-2-acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14-16kDa glycoprotein consisting of 134 amino acids with a single carbohydrate side chain at residue Asn13. BV-PLA2 displays 3 peptide T-cell epitopes and 1 glycopeptide T-cell epitope which are recognized by allergic and non-allergic bee venom-sensitized individuals. BV-PLA2 elicits IgE-mediated allergic responses in allergic individuals. References & CitationsTechnical Protocols Certificate of Analysis |
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