Recombinant Human FGF-4

Home/Recombinant Proteins/Recombinant Human FGF-4

Pricing & Details

Product. No.F128
Alternate Names
HST-1, Transforming Protein KS3, HBGF-4, HST, HSTF1, K-FGF, KFGF
Expression Host
E. coli
Prod No.
Add to cart
F128-25 µg
25 µg
In stock
Min: 1
Step: 1
F128-100 µg
100 µg
In stock
Min: 1
Step: 1
F128-500 µg
500 µg
In stock
Min: 1
Step: 1
F128-1 mg
1 mg
In stock
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.


Fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene), also known as FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-4 has an ability to promote neural stem cell proliferation and neuronal differentiation in the postnatal brain.1

Protein Details

>95% by SDS-PAGE and HPLC
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human FGF-4 was monitored in a mitogenic assay by measuring the FGF dependent 3H-thymidine incorporation in quiescent NR6R-3T3 fibroblasts (Thomas, K., 1987 Methods in Enzymology 147:120 - 135; Rizzino, A. et al., 1988, Cancer Res. 48:4266). The expected ED50 for this effect is typically 0.05 - 0.15 ng/mL.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
The DNA sequence encoding the putative mature 176 amino acid residue FGF-4 (excluding the 30 amino acid residue deduced signal peptide) was cloned into a suitable expression vector and expressed in E. coli (Delli Bovi, P. et al., 1987, Cell 50:729 - 737; Miyagawa, K. et al., 1988, Oncogene 3:383 - 389).
State of Matter
Predicted Molecular Mass
This preparation of Recombinant Human FGF-4 is subject to proteolytic cleavage, which results in a mixture of 4 peptides and reveals bands on an SDS PAGE gel at Mr 14 kDa & 16 kDa.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Ochiya T. et al. (2006) FASEB J. 20: 1848
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok