Recombinant Human GDF-5

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Pricing & Details

Product. No.G630
Alternate Names
CDMP1, LAP4, SYNS2
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
G630-50 µg
50 µg
$224.00
In stock
Max:
Min: 1
Step: 1
G630-100 µg
100 µg
$374.00
In stock
Max:
Min: 1
Step: 1
G630-500 µg
500 µg
$834.00
In stock
Max:
Min: 1
Step: 1
G630-1 mg
1 mg
$1,432.00
In stock
Max:
Min: 1
Step: 1

Background

Growth differentiation factor 5 (cartilage-derived morphogenetic protein-1), also known as GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF5 is expressed in the developing central nervous system.1 It increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease.2

Protein Details

Purity
>95% by SDS Page and HPLC
Endotoxin Level
<0.125 EU/µg
Biological Activity
Human GDF-5 is fully biologically active when compared to standard. Induction of alkaline phosphatase acrtivity in ATDC5 cells: EC50 = 40Nm.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Sullivan, A. et al. (2004) J Neurocytol 33: 479
2. O'Keeffe, G. et al. (2005) J Anat 207: 219
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
G630
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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