Recombinant Human ICAM-2

Recombinant Human ICAM-2

Product No.: I-589

[product_table name="All Top" skus="I-589"]

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Alternate Names
Inter-Cellular Adhesion Molecule 2, CD102
Product Type
Recombinant Protein
Expression Host
NS0 Cells
Species
Human

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Product Size
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Background

Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein.
This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Fusion Protein Tag
Fc Fusion Protein
Protein Accession No.
Amino Acid Sequence
dekvfevh vrpkklavep kgslevncst tcnqpevggl etslnkilld eqaqwkhylv snishdtvlq chftcsgkqe smnsnvsvyq pprqviltlq ptlvavgksf tiecrvptve pldsltlflf rgnetlhyet fgkaapapqe atatfnstad redghrnfsc lavldlmsrg gni (IEGRMD) (Human IgG1) hhhhhh
N-terminal Sequence Analysis
Lys25
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human ICAM-2 is Mr 50 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 86 kDa.
Predicted Molecular Mass
50
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4 containing calcium and magnesium with 1% sorbitol.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.