Recombinant Human ICAM-2

Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein.
This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

Fc Fusion Protein

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Lys25

Lyophilized

The predicted molecular weight of Recombinant Human ICAM-2 is Mr 50 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 86 kDa.

This recombinant protein was lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4 containing calcium and magnesium with 1% sorbitol.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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