Recombinant Human Interleukin 13 Receptor, Alpha 1 (IL-13 Rα1)

Recombinant Human Interleukin 13 Receptor, Alpha 1 (IL-13 Rα1)

Product No.: I-548

[product_table name="All Top" skus="I-548"]

- -
- -
Alternate Names
IL13RA1, CD213A1, IL-13Ra, NR4
Product Type
Recombinant Protein
Expression Host
NS0 Cells

- -
- -
Select Product Size
- -
- -


Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.1

Protein Details

>90% by SDS Page and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human IL-13 Rα1 was determined by its binding ability in a functional ELISA.
Protein Accession No.
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human IL-13 Rα1 is Mr 64 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 110 kDa.
Predicted Molecular Mass
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Caput, D. et al. (1996) J. Biol. Chem. 271:16921
2. Donaldson, DD. et al. (1998) J. Immunol. 161:2317
3. Hilton, DJ. et al. (1996) Proc. Natl. Acad. Sci. (USA) 93:497
4. Zhang, JG. et al. (1997) J. Biol. Chem. 272:9474
5. Orchansky, PL. et al. (1999) J. Biol. Chem. 274:0818
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.