Recombinant Human IL-31

Recombinant Human IL-31

Product No.: I-417

[product_table name="All Top" skus="I-417"]

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Alternate Names
Interleukin-31
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Select Product Size
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Background

Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Protein Accession No.
Amino Acid Sequence
shtlpvr llrpsddvqk iveelqslsk mllkdveeek gvlvsqnytl pclspdaqpp nnihspaira ylktirqldn ksvideiieh ldklifqdap etnisvptdt heckrfilti sqqfsecmdl alksltsgaq qatt
N-terminal Sequence Analysis
Ser24
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human IL-31 is Mr 15.8 kDa.
Predicted Molecular Mass
15.8
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Dillon, SR. et al.(2004) Nature Immunol. 5: 752
2. Homey, B. et al.(2006) J Allergy Clin Immunol. 117: 411

Certificate of Analysis

IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.