Recombinant Human IL-31

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Pricing & Details

Prod. No.I-417
Expression Host
E. coli
Size
Price
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10 µg
319.00
Max:
Min: 1
Step: 1

Background

Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
shtlpvr llrpsddvqk iveelqslsk mllkdveeek gvlvsqnytl pclspdaqpp nnihspaira ylktirqldn ksvideiieh ldklifqdap etnisvptdt heckrfilti sqqfsecmdl alksltsgaq qatt
N-terminal Sequence Analysis
Ser24
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human IL-31 is Mr 15.8 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Dillon, SR. et al.(2004) Nature Immunol. 5: 752
2. Homey, B. et al.(2006) J Allergy Clin Immunol. 117: 411
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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