Anti-Mouse IL-31 (NT)
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rabbit Immunogen PN:I-515 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2830714 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Anti-Mouse Interleukin-31 (IL-31) recognizes an epitope near the N-terminus of Mouse IL-31. This polyclonal antibody was purified using affinity chromatography. Background Interleukin-31 (IL-31) is a T-cell cytokine, which is preferentially produced by type 2 helper T cells. The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A and oncostatin M receptor subunits. IL-31 is believed to play a role in inflammation of the skin.1 IL-31 represents a novel target for antipruritic drug development.2 PubMed References & Citations1. Stacey R Dillon et al.(2004) Nature Immunol. 5: 752
2. Homey B. et al.(2006) J Allergy Clin Immunol. 117: 411
Technical ProtocolsCertificate of Analysis |
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