BackgroundProlactin Receptor (PRL-R) is a cytokine receptor that lacks an intrinsic kinase domain and relies on the cytoplasmic Jak tyrosine kinases to transduce signals (1). PRL-R is required for the signaling and proliferation of prolactin (2). Prolactin receptors have been localized in a number of peripheral tissues, including tissues involved in reproduction (3). Within the immune |