Recombinant Human SDF-1α

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Pricing & Details

Product. No.S111
Alternate Names
Stromal Cell-Derived Factor-1 Alpha, TLSF-a, CXCL12a, Pre-B Cell Growth Stimulating Factor (PBSF)
Expression Host
E. coli
Human/Rhesus Macaque/Feline
Prod No.
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S111-10 µg
10 µg
In stock
Min: 1
Step: 1
S111-50 µg
50 µg
In stock
Min: 1
Step: 1



SDF-1alpha (stromal cell-derived factor-1 alpha) is an alpha-chemokine for haematopoietic stem cells (HSC).4 SDF-1 alpha plays a role in two important processes of granule cell maturation - proliferation and migration - assisting in the achievement of appropriate cell number and position in the cerebellar cortex.5 SDF-1 alpha is also involved in the trafficking of hematopoietic progenitors and stem cells.6 It is expressed by liver cells and in liver diseases.7

Protein Details

≥95% by SDS Page
Endotoxin Level
≤ 1.0 EU/mg as determined by the LAL method
Biological Activity
The biological activity of Human SDF-1α was determined by its ability to chemoattract 5 - 10 day cultured human T-lymphocytes, or chemoattract BaF/3 hCXCR4 cells. The expected ED50 for these effects are typically 3 - 9 ng/ml, or 0.15 - 0.6 ng/ml, respectively.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
kpvslsyrc pcrffeshva ranvkhlkil ntpncalqiv arlknnnrqv cidpklkwiq eylekalnk
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human SDF-1α is Mr 8.0 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is 7 kDa (reducing conditions).
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Peiper, SC. et al. (2006) Methods Mol Biol. 332:115-27. Article Link
2. Peiper, SC. et al. (2005) Cancer Res.65(22):10450-6. Article Link
3. Peiper SC. et al. (2002) J Biol Chem. 277(27):24515-21. Article Link
4. Pei, G. et al. (2002) J Biol Chem. 277(51):49212-9. Article Link
5. Ratajczak MZ. et al. (2003) Folia Histochem Cytobiol. 41: 13
6. Luster AD et al. (2001) Development 128: 1971
7. Vannier JP et al. (2002) Eur Cytokine Netw 12: 223
8. James Dickenson et al. (2008) Iran J Allergy Asthma Immunol. 7: 61
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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