Recombinant Mouse gAcrp30 (Adipocyte Complement-Related Protein)

gAdiponectin (gAcrp30) is a adipocyte complement-related protein and is a member of the family of defense collagens.¹ gAdiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. The signaling receptors for adiponectin and gAcrp30 have recently been identified and named AdipoR1 and AdipoR2.² AdipoR1 is produced primarily in muscle while AdipoR2 is predominantly expressed in the liver. gAcrp30 is an anti-diabetic and anti-antherogenic hormone that plays important roles in the regulation of lipid and glucose metabolism.³

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Ala111 & Tyr112

Solution

The predicted molecular weight of Recombinant Mouse gAcrp30 is Mr 16.7 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 18-24 kDa (reducing conditions).

16.7

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This recombinant protein is stable for at least one month when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20 to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Dry Ice

1. Scherer, PE. et al. (1995) J. Biol. Chem. 270:26746
2. Yamauchi, T. et al. (2003) Nature 423:762
3. Hu, E. et al. (1996) J. Biol. Chem. 271:10697