CXCL15 is a small cytokine belonging to the CXC chemokine family that is highly abundant in epithelial cells of the lung1 and can also be found in other mucosal organs such as the urogenital and gastrointestinal tracts, and in endocrine organs like the adrenal gland. CXCL15 recruits neutrophils during pulmonary inflammation2 at which time it acts to specifically recruit neutrophils and direct them into the lung airway.
>90% by SDS-PAGE and analyzed by silver stain.
<0.01 EU/µg as determined by the LAL method
The biological activity of Mouse Lungkine is determined by its ability to chemoattract human neutrophils using a concentration range of 20.0-100.0 ng/ml.
Protein Accession No.
Amino Acid Sequence
mqelrc lciqehsefi plkliknimv ifetiycnrk eviavpkngs micldpdapw vkatvgpitn rflpedlkqk efppamklly svehekplyl sfgrpenkri fpfpiretsr hfadlahnsd rnflrdssev sltgsda
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse CXCL15 is Mr 16.5 kDa.
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA) with BSA as a carrier protein.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank
References & Citations
1. Zlotnik, A. et al. (1999) J Immunol. 162: 5490
2. Lorenz, RG. et al. (2007) J Histochem Cytochem. 55: 515
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.