Recombinant Mouse Macrophage Inflammatory Protein 1 Gamma (MIP-1γ)

Macrophage inflammatory protein 1 gamma (MIP-1 gamma) is a monokine with inflammatory, pyrogenic, and chemokinetic CC properties. MIP-1 gamma plays an important role in the differentiation and survival of osteoclasts.¹

The biological activity of Mouse MIP-1 γ (aa 50 - 122) was determined by its ability to chemoattract hCCR1 transfected mouse BaF/3 cells. The expected ED₅₀ for this effect is typically 0.2 - 1 ng/ml.

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Gly50

Lyophilized

The predicted molecular weight of Recombinant Mouse MIP-1 γ is Mr 8.4 kDa.

8.4

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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1. Stashenko, P.et al. (2004) J. Immunol. 173: 2084