Recombinant Mouse MIP-2

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Pricing & Details

Product. No.M174
Alternate Names
MIP-2, SCYB2, GRO2, Growth-Regulated Protein Beta (GROβ), MIP-2a, MGSA-b, CINC-2a, Cytokine-Induced Neutrophil Chemotactic Factor 3 (CINC-3), CXCL2
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
Add to cart
M174-10 µg
10 µg
$259.00
In stock
Max:
Min: 1
Step: 1
M174-50 µg
50 µg
$459.00
In stock
Max:
Min: 1
Step: 1

Background

Chemokine (C-X-C motif) ligand 2 (CXCL2) is an inducible murine chemokine involved in attraction of polymorphonuclear granulocytes to sites of infection.1 This chemokine is secreted by monocytes and macrophages and is chemotactic for hematopoietic stem cells.2,3,4

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Mouse MIP-2 was determined by its ability to induce myeloperoxidase release from human neutrophils or chemotaxis of hCXCR2 transfected mouse BaF/3 cells. The expected ED50 for these effects are typically 0.15 - 0.3 μg/ml or 0.1 - 0.5 ng/ml, respectively.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
avv aselrcqclk tlprvdfkni qslsvtppgp hcaqteviat lkggqkvcld peaplvqkii qkilnkgkan
N-terminal Sequence Analysis
Ala28
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse CXCL2 is Mr 8 kDa.
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Beuscher, HU. et al. (2004) International Immunol. 16: 1675
2. Cerami, A. et al. (1989) Proc Nat Acad Sci. 86: 612
3. Grotendorst, GR. et al. (1990) Mol Cell Biol. 10: 5596
4. Fukuda, S. et al. (2006) Exp Hematol. 34: 1010
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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