SDF-1 beta (stromal cell-derived factor-1 beta) is a non-glycosylated Polypeptide that is produced in E-Coli, belonging to the alpha chemokine (C-X-C) family of cytokines.1 SDF-1beta is a highly efficacious chemoattractant for resting lymphocytes and CD34(+) progenitor cells, and it efficiently blocks the CXCR-4-mediated entry into cells of T cell line tropic strains of HIV type 1 (HIV-1). SDF-1beta promotes HIV-1 replication and disease progression.2
>97% by SDS Page and HPLC
The biological activity of Mouse Stromal Cell-Derived Factor-1 Beta is determined by its ability to chemoattract human monocytes using a concentration range of 50.0-100.0 ng/ml.
Protein Accession No.
Amino Acid Sequence
KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM
State of Matter
Predicted Molecular Mass
The molecular weight of Recombinant Mouse SDF-1β is Mr 8.526 kDa.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
References & Citations
1. Muller HW et al. (2000) Eur J Neurosci. 12: 1857 2. Nagai Y et al. (1998) Proceedings of National Acad Sci USA 95: 6331
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.