Recombinant Mouse VEGF R2

Recombinant Mouse VEGF R2

Product No.: V120

[product_table name="All Top" skus="V120"]

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Alternate Names
Vascular Endothelial Growth Factor Receptor 2, KDR, Flk-1, CD309, VEGFR
Product Type
Recombinant Protein
Expression Host
NS0 Cells

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Vascular endothelial growth factor receptor 2 (VEGF R2) is a transmembrane glycoprotein that is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration, and differentiation.1,2,3

Protein Details

>90% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Mouse VEGF R2 was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells. The expected ED<sub>50</sub> for this effect is typically 10 - 30 ng/ml in the presence of 5 ng/ml of rmVEGF.
Fusion Protein Tag
Fc Fusion Protein
Protein Accession No.
Amino Acid Sequence
a svglpgdflh ppklstqkdi ltilanttlq itcrgqrdld wlwpnaqrds eervlvtecg ggdsifcktl tiprvvgndt gaykcsyrdv diastvyvyv rdyrspfias vsdqhgivyi tenknktvvi pcrgsisnln vslcarypek rfvpdgnris wdseigftlp symisyagmv fceakindet yqsimyivvv vgyriydvil sppheielsa geklvlncta rtelnvgldf twhsppsksh hkkivnrdvk pfpgtvakmf lstltiesvt ksdqgeytcv assgrmikrn rtfvrvhtkp fiafgsgmks lveatvgsqv ripvkylsyp apdikwyrng rpiesnytmi vgdeltimev terdagnytv iltnpismek qshmvslvvn vppqigekal ispmdsyqyg tmqtltctvy anpplhhiqw ywqleeacsy rpgqtspyac kewrhvedfq ggnkievtkn qyaliegknk tvstlviqaa nvsalykcea inkagrgerv isfhvirgpe itvqpaaqpt eqesvsllct adrntfenlt wyklgsqats vhmgesltpv cknldalwkl ngtmfsnstn dilivafqna slqdqgdyvc saqdkktkkr hclvkqliil ermapmitgn lenqtttige tievtcpasg nptphitwfk dnetlvedsg ivlrdgnrnl tirrvrkedg glytcqacnv lgcaraetlf iiegaqektn leiegrmdpk scdkthtcpp cpapellggp svflfppkpk dtlmisrtpe vtcvvvdvsh edpevkfnwy vdgvevhnak tkpreeqyns tyrvvsvltv lhqdwlngke ykckvsnkal papiektisk akgqprepqv ytlppsrdel tknqvsltcl vkgfypsdia vewesngqpe nnykttppvl dsdgsfflys kltvdksrwq qgnvfscsvm healhnhytq kslslspgkh hhhhh
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse VEGF R2 is Mr 110 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 166-191 kDa.
Predicted Molecular Mass
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Homqvist, K. et al. (2004) J Biol Chem. 279: 22267
2. Meyer, RD. et al. (2002) J Biol Chem. 277: 27081
3. Rahimi, N. et al. (2000) J Biol Chem. 275: 16986
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.