Anti-Mouse EDAR (Clone 132102)
Anti-Mouse EDAR (Clone 132102)
Product No.: E258
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Clone 132102 Target EDAR Formats AvailableView All Product Type Monoclonal Antibody Alternate Names DL, ED1R, ED3, ED5, EDA-A1R, EDA1R, EDA3, FLJ94390, Ectodysplasin A Receptor Isotype IgG2a Applications WB |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rat Immunogen NS0-Derived Recombinant Mouse EDAR Extracellular Domain Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2830030 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Mouse EDAR this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit for Mouse EDAR is 25 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rat Anti-Mouse Ectodysplasin A Receptor (EDAR) (Clone 132102) recognizes an epitope on Mouse EDAR. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Ectodysplasin A receptor, also known as EDAR is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. 1 EDAR is the genetic determinant of hair thickness as well as a strong contributor to hair fiber thickness variation among Asian populations. 2 PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Headon, DJ. et al. (2008)Hum Genet. 29:1405 2. Tokunaga, K. et al. (2008)Hum Genet. 124:179 Technical Protocols Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
