Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Product Concentration 1.0 mg/ml Formulation This purified antibody is supplied in 0.01 M phosphate buffered saline (PBS), pH 7.4, containing 0.09% sodium azide. Storage and Handling This Purified No Carrier Protein antibody is stable when stored at 2-8°C. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828040 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human Alpha-1 Fetoprotein (AFP) (Clone 166) recognizes Human Alpha-1 Fetoprotein. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Alpha-1-Fetoprotein (AFP) is a protein that is normally only produced in the fetus during its development. It is a normally produced by the liver and yolk sac of the fetus. AFP levels decrease soon after birth and probably has no function in normal adults. It binds the hormone estradiol to keep it from affecting the fetal brain. Its measurement during pregnancy has been useful to detect certain abnormalities - specifically, if high levels of AFP are found in amniotic fluid, it can indicate a developmental defect in the baby. In some patients who are not pregnant a tumor can produce AFP, thus it can be used as a tumor marker.
Antigen DetailsProtein PubMed |
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