Anti-Human CCR8 (EL)

Pricing & Details

Product No.C1119
Protein
CCR8
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
CC Chemokine Receptor-8, TER1, CKR-L1, Chem R1
Applications
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
C1119-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
C1119-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human CCR8 recognizes an epitope in the extracellular loop of Human CCR8. This polyclonal antibody was purified using affinity chromatography.
Background
CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and mouse CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

Antigen Details

Protein
PubMed

References & Citations

1. Napolitano, M. et al. (1996) J. Immunol. 157:2759 2. Zaballos, A. et al. (1996) Biochem. Biophys. Res. Commun. 227:846 3. Samson, M. et al. (1996) Eur. J. Immunol. 26:3021 4. Goya, I. et al. (1998) J. Immunol. 160:1975
General Western Blot Protocol
Prod No.
Description
C1119
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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