Anti-Human FGF-9

Product No.: F1070

[product_table name="All Top" skus="F1070"]

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Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Fibroblast Growth Factor-9, Growth Factor-9, GAF (Glia-Activating Factor), HBGF-9, HBFG-9, MGC119914, MGC119915

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Antibody Details

Product Details

Reactive Species
Host Species
Purified Recombinant Human FGF-9 (Accession # P31371)
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Storage and Handling
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Country of Origin
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 2-8 µg/ml. A suitable detection antibody is PN:F1093 at a concentration of approximately 0.1-0.4 µg/ml. A suggested standard for this assay is PN:F123.
Additional Applications Reported In Literature ?
Neutralization: This antibody is useful for neutralization of Human FGF-9 bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human FGF-9 (at 10 ng/ml) is 1-2 µg/ml.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.


Mouse Anti-Human Fibroblast Growth Factor 9 (FGF-9) (Clone 36912) recognizes an epitope on Human FGF-9. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Fibroblast growth factor 9 (glia-activating factor), also known as FGF9 is a glycosylated neurotrophic polypeptide highly expressed in brain.1 It is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. FGF-9 has sequence similarity of approximately 30% to other members of the family of fibroblast growth factors.2 It is highly related to FGF-16.
FGF-9 has been shown to mediate its effects by binding to FGF receptors. It efficiently activates the FGFR2c splice form of FGFR2 and the FGFR3b and FGFR3c splice isoforms of FGFR3.3 FGF-9 is a high affinity, heparin dependent ligand for FGFR3 and FGFR2 but not for FGFR1 and FGFR4.4

Antigen Details


References & Citations

1. Imamura, T. et al. (1999)J Biol Chem 274: 29352
2. Miyamoto, M. et al. (1993)Molecular Cellular Biology 13: 4251
3. Santos-Ocampo, S. et al. (1996)Journal of Biological Chemistry 271: 1726
4. Hecht, D. et al. (1995)Growth Factors 12: 223
Elisa Sandwich Protocol
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.