Anti-Human T-Cadherin (NT) (T-cad)

Pricing & Details

Product No.T275
Protein
T-cad
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
T-Cadherin, Cadherin-13 Precursor, Heart-Cadherin
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
T275-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
T275-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:T296
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human T-Cadherin (T-cad) recognizes an epitope near the N-terminus of Human, Mouse and Rat T-cad. This polyclonal antibody was purified using affinity chromatography.
Background
T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth.1 T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage.2 T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers.3,4 Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Antigen Details

Protein
PubMed

References & Citations

1. Ranscht, B. et al. (1991) Neuron 7:391
2. Ivanov, DB. et al. (2001) Biochemistry (Moscow) 66:1175
3. Takeuchi, T. et al. (1999) Histopathology 35:87
4. Sato, M. et al. (1998) Hum. Gen. 103:96
IHC
General Western Blot Protocol
Prod No.
Description
T275
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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