Anti-Quinidine Mouse Monoclonal Antibody – Library Pack (165101)
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Quinidine is a class I antiarrhythmic agent. - -
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DescriptionBackground Quinidine is a class I antiarrhythmic agent. Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa) which causes the phase 0 depolarization of the cardiac action potential to decrease (decreased Vmax). Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na /K -ATPase by binding to the same receptor sites as the digitalis glycosides such as ouabain. Immunogen Quinidine conjugated to KLH. Specificity Selection of Mouse Monoclonal antibodies specific to Quinidine. Product Preparation Antibodies are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Kit DetailsMaterials Provided Anti-Quinidine Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies: 16501 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-228.6.5 - Isotype IgG2b 16502 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-261.3.6 - Isotype IgG1 16503 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD11-265.2.3 - Isotype IgG1 16504 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD13-406.6.1 - Isotype IgG1 16505 - Anti-Quinidine Mouse Monoclonal Antibody - Clone QD14-504.5 - Isotype IgG1 Storage & Stability Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles. Technical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
