Anti-RSV RSS-2 [Polyclonal]

Product No.: 15900

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Target
Respiratory Syncytial Virus
Product Type
Polyclonal
Isotype
Rabbit
Applications
WB

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Antibody Details

Product Details

Reactivity Species
Respiratory Syncytial Virus
Host Species
Rabbit
Immunogen
Peptide corresponding to amino acids 201-211 of the 63 kD Respiratory Syncytial Virus (RSV) fusion protein of the RSS-2 strain (subtype A).
Product Concentration
Lot Specific
Formulation
PBS, pH 7.4 with 0.02% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
It is recommended to aliquot the undiluted antibody into smaller working volumes (e.g., 10–30 µL per vial, depending on usage) upon receipt. For long-term storage, keep aliquots at –20°C or –80°C. Maintain a separate working aliquot at 4°C for short-term use. Avoid repeated freeze/thaw cycles to preserve antibody integrity. When properly stored, the antibody remains stable for a minimum of one year.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1:500-1:1,000.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
This Rabbit Polyclonal Antibody is specific to 63 kDa RSV F protein
Background
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in infants and young children worldwide. RSV infection can produce a wide range of symptoms, affecting various regions of the respiratory system—from the nasal passages to the lungs—and may lead to conditions such as bronchiolitis and pneumonia.

RSV is an enveloped, negative-sense, single-stranded RNA virus belonging to the Pneumoviridae family. The virions are pleomorphic, meaning they vary in shape and size, typically ranging from 120 to 300 nanometers in diameter.

A key component of RSV pathogenesis is the 63 kDa fusion (F) protein, particularly from the RSV A2 strain (subtype A). This surface glycoprotein mediates fusion of the viral envelope with host cell membranes, facilitating viral entry. In addition to enabling infection, the F protein can also promote cell-cell fusion, leading to the formation of syncytia—large, multinucleated cells characteristic of RSV infection and a hallmark of its cytopathic effect.

Antigen Details

Research Area
Infectious Disease

References & Citations

General Western Blot Protocol
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.