Apoptosis Signal-Regulating Kinase (CT-2) Blocking Peptide
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration 0.2 mg/ml Amino Acid Location 16 amino acids near the carboxy terminus of human ASK1. Formulation This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Storage and Handling Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Amino Acid Sequence 16 amino acids near the carboxy terminus of human ASK1. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Background Apoptosis Signal-Regulating Kinase peptide is applicable as a control peptide for blocking antibody binding in Western blotting. Antigen DetailsReferences & Citations1. Wang XS, Diener K, Jannuzzi D, et al. Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J. Biol. Chem. 1996; 271:31607-11.
2. Van Kooten C and Bancherau J. CD40-CD40 ligand. J. Leukoc. Biol. 2000; 67:2-17.
3. Grech AP, Amesbury M, Chan T, et al. TRAF2 differentially regulates the canonical and noncanonical pathways of NF-κB activation in mature B cells. Immunity 2004; 21:629-42.
4. Davies CC, Mak TW, Young LS, et al. TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells. Mol. Cell. Biol. 2005; 25:9806-19. 5. Kuai J, Nickbarg E, Wooters J, et al. Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin-? receptor reveals a novel mechanism of apoptosis. J. Biol. Chem. 2003; 278:14363-9. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
