Recombinant Human CD23 (Soluble)

Recombinant Human CD23 (Soluble)

Product No.: C1318

[product_table name="All Top" skus="C1318"]

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Alternate Names
FCER2, CD23A, CLEC4J, FCE2, IGEBF, OKT10, Leu20, B6, or Blast-2, 18.6 Antigen
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Product Size
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Background

CD23 (cluster of differentiation 23), also known as Fc epsilon RII or FcεRII, is a type 2 transmembrane C-type lectin and a member of the Ig family that is expressed on most mature B cells. CD23 is a surface marker of activated B cells as well as a low-affinity Fc receptor for IgE.1 CD23 has pleiotropic roles in the control of lymphocyte behaviour, suggesting that CD23 may interact with another ligand in addition to IgE.2 CD23 is important in the differentiation of chronic lymphocytic leukemia (CLL) from other lymphoid leukemias.3

Protein Details

Purity
>95% by SDS-PAGE and HPLC
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Protein Accession No.
Amino Acid Sequence
MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
State of Matter
Lyophilized
Predicted Molecular Mass
The molecular weight of Recombinant Human sCD23 is Mr 19.2 kDa.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Sakai, H. et al. (1992) Nephron 60: 404
2. Jean-Yves et al. (1992) Nature 358: 505
3. Keating, M. et al. (2002) Cancer 94: 172
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.