Recombinant Human EG-VEGF

Recombinant Human EG-VEGF

Product No.: V108

[product_table name="All Top" skus="V108"]

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Alternate Names
Endocrine-Gland-Derived Vascular Endothelial Cell Growth Factor, Prokineticin 1, PROK1, PK1
Product Type
Recombinant Protein
Expression Host
NS0 Cells
Species
Human

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Select Product Size
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Background

Endocrine Gland-Derived Vascular Endothelial Growth Factor (EG-VEGF/PK-1) is a member of the prokineticin family of secreted proteins. It is expressed in various tissues including the GI tract and steroidogenic glands (1). EG-VEGF promotes angiogenesis acting via two G-protein coupled receptors, PK-R1 and PK-R2 (2). EG-VEGF results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration, and survival of responsive endothelial cells (3).

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Fusion Protein Tag
Histidine Tag
Protein Accession No.
Amino Acid Sequence
a vitgacerdv qcgagtccai slwlrglrmc tplgregeec hpgshkvpff rkrkhhtcpc lpnllcsrfp dgryrcsmdl kninfhhhhh h
N-terminal Sequence Analysis
Ala20
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human EG-VEGF is Mr 10.5 kDa.
Predicted Molecular Mass
10.5
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) with BSA as a carrier protein. pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Meidan, R. et al. (2005) Endocrinology. 146(9):3950-8.
2. Ferrara, N. et al. (2002) Cold Spring Harb Symp Quant Biol.67:217-21.
3. Ferrara, N. et al. (2002) J Biol Chem. 277(10):8724-9.

Certificate of Analysis

IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.