Recombinant Human MIA-2
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Antibody DetailsProduct DetailsReactive Species Human Expression Host E. coli Cells Endotoxin Level <0.1 EU/µg as determined by the LAL method Purity >98% by SDS Page and HPLC State of Matter Lyophilized Storage and Handling The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Amino Acid Sequence MLESTKLLAD LKKCGDLECE ALINRVSAMR DYRGPDCRYL NFTKGEEISV YVKLAGERED LWAGSKGKEF GYFPRDAVQI EEVFISEEIQ MSTKESDFLC L Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Background Melanoma Inhibitory Activity 2 (MIA-2) is a secreted protein1 that is a member of the MIA gene family.2 MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells. MIA-2 is selectively expressed in hepatocytes.1 It may serve as a marker of hepatic disease activity and severity.3 Antigen DetailsPubMed References & Citations1. Bosserhoff, AK. et al. (2005) Liver Int. 25: 357 2. Bosserhoff, AK. et al. (2008) Gut 57: 243 3. Hellerbrand, C. et al. (2003) J Biol Chem. 278: 15225 |
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