Recombinant Human Persephin

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Pricing & Details

Product. No.P136
Alternate Names
PSPN
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
P136-5 µg
5 µg
$221.00
In stock
Max:
Min: 1
Step: 1
P136-20 µg
20 µg
$347.00
In stock
Max:
Min: 1
Step: 1

Background

Persephin (PSP) is a secreted protein belonging to the glial cell line-derived neurotrophic factor (GDNF) family of the TGF-b superfamily. Just like factor GDNF and neurturin (NTN), PSP promotes the survival of ventral midbrain dopaminergic neurons and prevents their degeneration. Persephin also supports the survival of motor neurons.1 Persephin is expressed at very low levels in most tissues. It is synthesized throughout the nervous system and has both astroglial and neuronal origin.2

Protein Details

Purity
>95% by SDS Page and analyzed by silver stain.
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Expression Host
E. coli
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human PSP is Mr 10.3 kDa.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Johnson EM et al. (1998) Neuron 20: 245 2. Krieglstein K. et al. (1998) J Neurosci Res. 53: 494
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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