Recombinant Human SDF-1β

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Recombinant Human SDF-1β

Product No.: S110

[product_table name="All Top" skus="S110"]

Product. No.S110
Alternate Names
Stromal Cell-Derived Factor-1β, Thymic Lymphoma Cell Stimulating Factor-Beta (TLSF-β), CXCL12, Pre-B Cell Growth-Stimulating Factor (PBSF)
Product Type
Recombinant Protein
Expression Host
E. coli Cells

Product Size


SDF-1 beta (stromal cell-derived factor-1 beta) is a non-glycosylated Polypeptide that is produced in E-Coli, belonging to the alpha chemokine (C-X-C) family of cytokines.1 SDF-1beta is a highly efficacious chemoattractant for resting lymphocytes and CD34(+) progenitor cells, and it efficiently blocks the CXCR-4-mediated entry into cells of T cell line tropic strains of HIV type 1 (HIV-1). SDF-1beta promotes HIV-1 replication and disease progression.2

Protein Details

>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human SDF-1β was determined by its ability to chemoattract mouse BaF/3 cells transfected with hCXCR-4 and human T-lymphocytes cultured for 5 - 10 days. The expected ED50 for these effects are typically 1-5 ng/ml and 10-30 ng/ml, respectively.
Protein Accession No.
Amino Acid Sequence
kpvslsyrc pcrffeshva ranvkhlkil ntpncalqiv arlknnnrqv cidpklkwiq eylekalnkr fkm
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human SDF-1β is Mr 8 kDa.
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Muller, HW. et al. (2000) Eur J Neurosci. 12: 1857
2. Nagai, Y. et al. (1998) Proceedings of National Acad Sci USA 95: 6331
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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