Recombinant Human Transforming Growth Factor-Beta 3 (TGF-beta 3)
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BackgroundTransforming growth factor-beta 3 (TGF-beta 3) is a member of the TGF beta family of growth factors. It is involved in oxygen-dependent differentiation processes during placental development and pregnancy disorders.1 It also play an important role in wound repair and scarring.2 Protein DetailsFormat Purified No Carrier Protein Purity >90% by SDS-PAGE and HPLC Endotoxin Level <0.125 EU/µg as determined by the LAL method Biological Activity TGF-beta 3 is fully biologically active when compared to standard. The ED50 as determined by the cell toxicity assay using the WHO Standard 98/608 as a direct comparison is <0.05ng/ml, corresponding to a Specific Activity of 12.5 x 10<sup>6</sup> IU/mg. Protein Accession No. Amino Acid Sequence ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS N-terminal Sequence Analysis Met State of Matter liquid Family and Structure TGF Predicted Molecular Mass 11 kd Formulation Carrier Free PBD Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Mustoe, TA. et al. (1997) Arch Surg. 132: 753 2. Wenger, RH. et al. (2003) Placenta 24: 941 IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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