Recombinant Human Transforming Growth Factor-Beta 3 (TGF-beta 3)

Recombinant Human Transforming Growth Factor-Beta 3 (TGF-beta 3)

Product No.: T355

[product_table name="All Top" skus="T355"]

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Alternate Names
TGFB3, ARVD, FLJ16571
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Background

Transforming growth factor-beta 3 (TGF-beta 3) is a member of the TGF beta family of growth factors. It is involved in oxygen-dependent differentiation processes during placental development and pregnancy disorders.1 It also play an important role in wound repair and scarring.2

Protein Details

Format
Purified No Carrier Protein
Purity
>90% by SDS-PAGE and HPLC
Endotoxin Level
<0.125 EU/µg as determined by the LAL method
Biological Activity
TGF-beta 3 is fully biologically active when compared to standard. The ED50 as determined by the cell toxicity assay using the WHO Standard 98/608 as a direct comparison is <0.05ng/ml, corresponding to a Specific Activity of 12.5 x 10<sup>6</sup> IU/mg.
Protein Accession No.
Amino Acid Sequence
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
N-terminal Sequence Analysis
Met
State of Matter
liquid
Family and Structure
TGF
Predicted Molecular Mass
11 kd
Formulation
Carrier Free PBD
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Mustoe, TA. et al. (1997) Arch Surg. 132: 753
2. Wenger, RH. et al. (2003) Placenta 24: 941
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.