Transforming growth factor-beta 3 (TGF-beta 3) is a member of the TGF beta family of growth factors. It is involved in oxygen-dependent differentiation processes during placental development and pregnancy disorders.1 It also play an important role in wound repair and scarring.2
Purified No Carrier Protein
>90% by SDS-PAGE and HPLC
<0.125 EU/µg as determined by the LAL method
TGF-beta 3 is fully biologically active when compared to standard. The ED50 as determined by the cell toxicity assay using the WHO Standard 98/608 as a direct comparison is <0.05ng/ml, corresponding to a Specific Activity of 12.5 x 106 IU/mg.
Protein Accession No.
Amino Acid Sequence
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
N-terminal Sequence Analysis
State of Matter
Family and Structure
Predicted Molecular Mass
Carrier Free PBD
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
Next Day Ambient
NCBI Gene Bank
References & Citations
1. Mustoe, TA. et al. (1997) Arch Surg. 132: 753
2. Wenger, RH. et al. (2003) Placenta 24: 941
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.