Human CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity.
>97% by SDS-PAGE and analyzed by silver stain.
<0.01EU/µg as determined by the LAL method
Protein Accession No.
Amino Acid Sequence
sqregsled hqtdssisfl phleakirqt hnlarlltky aeqlleeyvq qqgepfglpg fspprlplag lsgpapshag lpvserlrqd aaalsvlpal ldavrrrqae lnpraprllr sledaarqvr algaavetvl aalgaaargp gpepvtvatl ftanstagif sakvlgfhvc glygewvsrt egdlgqlvpg gva
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse CT-1 is Mr 21 kDa.
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.