Recombinant Mouse Leptin R

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Pricing & Details

Product. No.L197
Alternate Names
Leptin Receptor, OB-R, B219, LEPR, CD295
Expression Host
NS0 cells
Species
Mouse
Prod No.
Size
Price
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Qty
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L197-100 µg
100 µg
$399.00
In stock
Max:
Min: 1
Step: 1

Background

Leptin receptor, also known as LEPR, and CD295 (cluster of differentiation 295) is a single-transmembrane-domain receptor of the cytokine-receptor family.1 Leptin receptor exists in multiple forms with a common extracellular domain and a variable length cytoplasmatic portion. Leptin receptor may act as a negative regulator of Leptin activity and it may maintain a pool of available bioactive Leptin by binding and delaying its clearance from circulation. Leptin receptor is considered a physiological marker of primate fetal lung maturity.2

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01 EU/µg as determined bythe LAL method
Fusion Protein Tag
Fc Fusion Protein
Expression Host
NS0 cells
Protein Accession No.
Amino Acid Sequence
a alnlaypisp wkfklfcgpp nttddsflsp agapnnasal kgaseaivea kfnssgiyvp elsktvfhcc fgneqgqncs altdntegkt lasvvkasvf rqlgvnwdie cwmkgdltlf ichmeplpkn pfknydskvh llydlpevid dsplpplkds fqtvqcncsl rgcechvpvp raklnyallm yleitsagvs fqsplmslqp mlvvkpdppl glhmevtddg nlkiswdsqt mapfplqyqv kylenstivr eaaeivsats llvdsvlpgs syevqvrskr ldgsgvwsdw sspqvfttqd vvyfppkilt svgsnasfhc iyknenqiis skqivwwrnl aekipeiqys ivsdrvskvt fsnlkatrpr gkftydavyc cneqachhry aelyvidvni niscetdgyl tkmtcrwsps tiqslvgstv qlryhrrsly cpdspsihpt sepkncvlqr dgfyecvfqp ifllsgytmw irinhslgsl dspptcvlpd svvkplppsn vkaeitvntg llkvswekpv fpennlqfqi ryglsgkeiq wkthevfdak sksasllvsd lcavyvvqvr crrldglgyw snwsspaytl vmdvkvpmrg pefwrkmdgd vtkkernvtl lwkpltknds lcsvrryvvk hrtahngtws edvgnrtnlt flwtepahtv tvlavnslga slvnfnltfs wpmskvsave slsayplsss cvilswtlsp ddysllylvi ewkilneddg mkwlripsnv kkfyihdnfi piekyqfsly pvfmegvgkp kiingftkda idkqqndagi iegrdmdpks cdkthtcppc papellggps vflfppkpkd tlmisrtpev tcvvvdvshe dpevkfnwyv dgvevhnakt kpreeqynst yrvvsvltvl hqdwlngkey kckvsnkalp apiektiska kgqprepqvy tlppsrdelt knqvsltclv kgfypsdiav ewesngqpen nykttppvld sdgsfflysk ltvdksrwqq gnvfscsvmh ealhnhytqk slslspgkhh hhhh
N-terminal Sequence Analysis
Ala20
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse Leptin R is Mr 120 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 150-170 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from a sterile solution containing Tris.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Guy-Grand, B. et al. (1998) Nature 392: 398
2. Castracane, VD. et al. (2004) Reproduction 127: 87
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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