Recombinant Rat VEGF164

Home/Recombinant Proteins/Recombinant Rat VEGF164

Pricing & Details

Product. No.V114
Alternate Names
Vascular Endothelial Growth Factor 164, VEGFA, MGC70609, VPF, VAS, Folliculostellate Cell-Derived Growth Factor, Glioma-Derived Endothelial Cell Mitogen
Expression Host
NS0 cells
Species
Rat
Prod No.
Size
Price
Avail.
Qty
Add to cart
V114-10 µg
10 µg
$349.00
In stock
Max:
Min: 1
Step: 1
V114-50 µg
50 µg
$949.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Background

Vascular endothelial growth factor (VEGF), a potent proangiogenic cytokine1 is the key signal used by oxygen-hungry cells to promote growth of blood vessels. It binds to specialized receptors on the surfaces of endothelial cells and directs them to build new vessels.2 The alternative splicing of mRNA from a single 8-exon VEGFA gene results in multiple isoforms which are classified by their terminal exon splice site. The classification depends on whether this terminal exon (exon-8) is proximal or distal. VEGF164 refers to the proximal splice site and contains one fewer amino acid than its human ortholog. VEGF are crucial regulators of vascular development during embryogenesis (vasculogenesis) and blood-vessel formation in the adult (angiogenesis). Abnormal VEGF function is associated with inflammatory diseases including atherosclerosis, and hyperthyroidism.3,4,5,6

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Expression Host
NS0 cells
Protein Accession No.
Amino Acid Sequence
aptt egeqkahevv kfmdvyqrsy crpietlvdi fqeypdeiey ifkpscvplm rcagccndea lecvptsesn vtmqimrikp hqsqhigems flqhsrcecr pkkdrtkpen hcepcserrk hlfvqdpqtc kcsckntdsr ckarqlelne rtcrcdkprr
N-terminal Sequence Analysis
Ala27
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Rat VEGF164 is Mr 19.2 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 25 kDa.
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Folkman, J. et al. (2008) FASEB J. 22: 3728
2. Goodsell, DS. et al. (2002) The Oncologist 7: 569
3. Mugishima, H. et al. (2006) J Atheroscler Thromb. 13: 130
4. Claesson-Welsh, L. et al. (2006) Exp Cell Res. 312: 549
5. Claesson-Welsh, L. et al. (1999) Trends Biochem Sci. 28: 488
6. Ellis, LM. et al. (2005) J Clin Oncol. 23: 1011
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
V102
V114
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok