Anti-PSDR1 Antibody (34007)
Anti-PSDR1 Antibody (34007)
Product No.: 34007
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Target PSDR1 Product Type Polyclonal Alternate Names EC 1.1.1.300, Androgen-regulated short-chain dehydrogenase/reductase 1, HCV core-binding protein HCBP12, Prostate short-chain dehydrogenase/reductase 1, Retinal reductase 1, RalR1, Short chain dehydrogenase/reductase family 7C member 1 Isotype Rabbit Applications ELISA , WB |
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen N-terminal sequence MVELMFP and C-terminal sequence LLGLPID of human PSDR1. Product Concentration Lot Specific Formulation PBS, pH 7.4 with 0.02% sodium azide State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at 1:500-1:1,000 dilution
ELISA: use at 1:1,000-1:5,000 dilution. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to PSDR1 Background Genes regulated by androgenic hormones are of critical importance for the normal physiological function of the human prostate gland, and they contribute to the development and progression of prostate cancer. PSDR1 (prostate short-chain dehydrogenase- reductase 1) is a novel gene whose expression is increased following exposure of LNCaP cells to androgens. PSDR1 is highly expressed in the human prostate gland and is localized in both normal and neoplastic prostate epithelium. It has been suggested that PSDR1 may play a role in the pathogenesis of prostate cancer. Antigen DetailsFunction Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12226107, PubMed:12036956, PubMed:29410696). Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal (PubMed:15865448). Has no dehydrogenase activity towards steroid (PubMed:12226107, PubMed:12036956). {PubMed:12036956, PubMed:12226107, PubMed:15865448, PubMed:29410696}. NCBI Gene Bank ID UniProt.org Research Area Cancer Research References & CitationsTechnical Protocols  |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
