Anti-Mouse IgA Antibody, HRP conjugate (80405)
- -
- -
Antibody DetailsProduct DetailsReactivity Species Mouse Host Species Goat Immunogen Mouse IgA Product Concentration 1.0 mg/ml Formulation Phosphate Buffered Saline (PBS) containing 0.2% BSA and 0.05% Pro-Clean 400 State of Matter Liquid Product Preparation Purified by affinity chromatography on mouse IgA Storage and Handling This antibody is stable for at least 1 year at 2-8°C. Regulatory Status For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at a dilution of 1:2,000-1:20,000.
Immunohistochemistry: use at a dilution of 1:200-1:2,000 Immunocytochemistry: use at a dilution of 1:200-1:2,000 ELISA: use at a dilution of 1:10,000-1:100,000. These are recommended dilutions. End users should determine optimal dilutions for their applications. Prepare working dilutions immediately before use. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity This polyclonal antibody is affinity-purified. Cross-reactivity with mouse IgM, IgG1, IgG2a, IgG2b, IgG2c, IgG3, and IgE is not detectable. Background Immunoglobulin A (IgA) is a crucial antibody primarily found in a dimeric form, meaning two IgA molecules are linked together by a J-chain protein. This unique structure allows IgA to play a vital role in mucosal immunity, protecting surfaces exposed to the external environment. You'll find IgA concentrated in areas rich in mucous membranes, such as the gut, respiratory system, eyes, and in colostrum (the first form of milk produced by mammals after birth). IgA exists in two main forms: Secretory IgA (sIgA): This is the predominant form found in mucosal secretions. Its specialized structure makes it highly resistant to degradation, allowing it to effectively neutralize pathogens on mucosal surfaces. Serum IgA: This monomeric form circulates in the bloodstream and plays a role in systemic immunity. Detecting Human IgA with Goat Anti-Human IgA-HRP Our Goat Anti-Human IgA-HRP conjugate is an ideal tool for detecting human IgA in various research applications. This secondary antibody is generated in goats and specifically targets human IgA. It's pre-conjugated to Horseradish Peroxidase (HRP), an enzyme that enables chromogenic or chemiluminescent detection when a suitable substrate is added. This makes our Goat Anti-Human IgA-HRP conjugate particularly useful for techniques like Western blotting, ELISA, and immunohistochemistry to identify and quantify human IgA. Antigen DetailsResearch Area Secondary Antibodies References & CitationsTechnical Protocols ICC   |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
