Anti-Bovine PKC Agarose

Pricing & Details

Product No.P110
Clone
MC5
Protein
Protein Kinase C
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
Mouse
IgG2a
Prod No.
Size
Price
Avail.
Qty
Add to cart
P110-1.0 ml
1.0 ml
$485.00
In stock
Max:
Min: 1
Step: 1

Antibody Details

Product Details

Reactivity Species
Bovine
Host Species
Mouse
Formulation
Anti-Protein Kinase C-Agarose is supplied in 0.01 M phosphate buffered saline (PBS) pH 7.2, 0.09% sodium azide as a preservative.
Storage and Handling
Stable when stored at 2 - 8°C.
Country of Origin
USA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Protein Kinase C (PKC) recognizes the intact (Mr 79-80 kDa) calcium-activated, phospholipid-dependent Protein Kinase C in bovine brain. The antibody strongly cross-reacts with PKC in human, mouse and rat cells.1 Anti-PKC (clone MC5) binds to an epitope at the hinge region of the enzyme, the site of phorbol-ester-induced proteolysis which is thought to down-regulate PKC activity in intact cells.1,2 Monoclonal MC5 reacts with PKC-α/ß12 isoforms.
Background
Anti-Protein Kinase C (PKC) has been covalently conjugated to 4% cross-linked agarose using conjugation chemistries to reduce non-specific binding and optimize binding of Protein Kinase C. Anti-Protein Kinase C-Agarose may be used to isolate Protein Kinase C.

Bead Size
75-300 µm (50-200 mesh)

Antigen Details

Research Area
Apoptosis
.
Cell Biology
.
Immunology

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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