Antibody DetailsProduct DetailsReactivity Species Bovine Host Species Mouse Formulation Anti-Protein Kinase C-Agarose is supplied in 0.01 M phosphate buffered saline (PBS) pH 7.2, 0.09% sodium azide as a preservative. Storage and Handling Stable when stored at 2 - 8°C. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831510 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Protein Kinase C (PKC) recognizes the intact (Mr 79-80 kDa) calcium-activated, phospholipid-dependent Protein Kinase C in bovine brain. The antibody strongly cross-reacts with PKC in human, mouse and rat cells.1 Anti-PKC (clone MC5) binds to an epitope at the hinge region of the enzyme, the site of phorbol-ester-induced proteolysis which is thought to down-regulate PKC activity in intact cells.1,2 Monoclonal MC5 reacts with PKC-α/ß1/ß2 isoforms. Background Anti-Protein Kinase C (PKC) has been covalently conjugated to 4% cross-linked agarose using conjugation chemistries to reduce non-specific binding and optimize binding of Protein Kinase C. Anti-Protein Kinase C-Agarose may be used to isolate Protein Kinase C.
Bead Size
75-300 µm (50-200 mesh)
Antigen DetailsProtein PubMed Research Area Apoptosis . Cell Biology . Immunology |
Formats Available
Prod No. | Description |
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P321 |
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P322 |
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P323 |
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P325 |
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P326 |
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P327 |
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P107 |
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P108 |
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P109 |
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P110 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.