Anti-CNS Myelin/Oligodendrocytes

Pricing & Details

Product No.D103
Clone
CE1
Protein
Oligodendrocytes
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Clone AERA8-154, CNS Myelin
Isotype
Mouse
IgM
Applications
IHC FFPE
Prod No.
Size
Price
Avail.
Qty
Add to cart
D103-0.125 mg
0.125 mg
$400.00
In stock
Max:
Min: 1
Step: 1

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-CNS Myelin/Oligodendrocytes (Clone AERA8-154 (CE1)) recognizes Myelin and Oligodendrocytes in the CNS. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
The MOSP antigen is present on oligodendrocytes and CNS myelin but not on Schwann cells or peripheral nervous system (PNS) myelin. No specific staining is observed in sections from PNS, retina, liver, skin, or kidney.
Background
Myelin is an electrically-insulating dielectric phospholipid layer that surrounds the axons of many neurons. It is an outgrowth glial cell: Schwann cells supply the myelin for peripheral neurons, whereas oligodendrocytes supply it to those of the central nervous system. Myelin is considered a defining characteristic of the (gnathostome) vertebrates, but it has also arisen by parallel evolution in some invertebrates. Myelin made by different cell types varies in chemical composition and configuration, but performs the same insulating function. Myelinated axons are white in appearance. Myelin is composed of about 80% lipid fat and about 20% protein. Some of the proteins that make up myelin are Myelin basic protein (MBP), Myelin oligodendrocyte glycoprotein (MOG), and Proteolipid protein (PLP).

Antigen Details

Research Area
Cell Biology
.
Neuroinflammation
.
Neuroscience
.
Neuroscience Cell Markers

References & Citations

1. Dyer, C. A. et al. (1991) J. of Neuroscience 28:607
IHC

Formats Available

Prod No.
Description
D103
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Cookie Policy
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy.