Anti-Hemoglobin (Human) Mouse Monoclonal Antibody – Library Pack (190101)
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DescriptionBackground Hemoglobin is the iron-containing oxygen-transport metalloprotein in red blood cells of all vertebrates as well as in the tissues of some invertebrates. In mammals, hemoglobin makes up about 35% of the total content of red blood cells. It has an oxygen-binding capacity of 1.34 mL O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood. The mammalian hemoglobin molecule can bind up to four oxygen molecules. Hemoglobin also carries some of the body's respiratory carbon dioxide (about 20–25% of the total) as carbaminohemoglobin as well as nitric oxide bound to a thiol group, releasing it at the same time as oxygen. Other cells that contain hemoglobin include the A9 dopaminergic neurons in the substantia nigra, macrophages, alveolar cells, and mesangial cells in the kidney. In these tissues, hemoglobin has a non-oxygen-carrying function as an antioxidant and a regulator of iron metabolism. Immunogen Purified human hemoglobin Specificity These antibodies recognize human hemoglobin. They do not cross-react with hemoglobin of the following species: bovine, chicken, equine, ovine, or porcine. Product Preparation Antibodies are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. Kit DetailsMaterials Provided Anti-Hemoglobin (Human) Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies: 19001 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-201.11 - Isotype IgG1 19002 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-203.1 - Isotype IgG1 19003 - Anti-Hemoglobin (Human) Mouse Monoclonal Antibody - Clone HB11-231.2 - Isotype IgG1 Storage & Stability Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles. Technical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.