Anti-Human Desmoglein-2

Anti-Human Desmoglein-2

Product No.: D350

[product_table name="All Top" skus="D350"]

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Product Type
Polyclonal Antibody
Alternate Names
Desmoglein-2, ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037

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Antibody Details

Product Details

Reactive Species
Host Species
NS0-Derived Recombinant Human Desmoglein-2 Extracellular Domain
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
State of Matter
Storage and Handling
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Country of Origin
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
Western Blotting: To detect Human Desmoglein-2 this polyclonal antibody can be used at a concentration of 0.25 µg/ml. This polyclonal antibody should be used in conjunction with compatible second-step reagents such as PN:G505 and a chromogenic substrate such as PN:T343. The detection limit for Human Desmoglein-2 is 1 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.


Goat Anti-Human Desmoglein-2 (DSG2) recognizes Human DSG2. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
Desmoglein 2, also known as DSG2, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. It provides cellular adhesion and forces transduction by cell-to-cell anchorage. 1 It also plays a role in embryonic stem cell proliferation.

Antigen Details

NCBI Gene Bank ID

References & Citations

1. Lieber, André et al. (2013) J Virol. 87(21): 11346–11362. PubMed
2. Ozcelik, C. et al.(2008) Mol Genet Metab. 95(1-2):74-80.
General Western Blot Protocol
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Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.