Anti-Human F1A-α (CT)

Pricing & Details

Product No.F143
Protein
F1A-α
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
FEM1-β
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
F143-20 µg
20 µg
$95.00
In stock
Max:
Min: 1
Step: 1
F143-0.1 mg
0.1 mg
$440.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:F144
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human F1A-α recognizes an epitope near the C-terminus of mouse, rat and human F1A-α. This polyclonal antibody was purified using affinity chromatography.
Background
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aα and FEM1b.1,2 F1Aα/FEM1β is the homologue of C. elegans sex determining protein FEM-1.1,2 FEM-1/F1Aα is cleaved by CED-3 and caspase.3 FEM-1/F1Aα associates with CED-4 and its mammalian homologue Apaf-1.3 Overexpression of F1Aα induces apoptosis. F1Aα is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aα is expressed in a variety of human and mouse tissues.1,2

Antigen Details

Protein
PubMed

References & Citations

1. Chan, SL. et al. (1999) J Biol Chem. 274(45):32461-8.
2. Ventura-Holman, T. and Maher, JF. (2000) Biochem Biophys Res Commun 267(1):317-20
3. Chan, SL. et al. (2000) J Biol Chem. 275 (24):17925-8.
IHC
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok