Anti-Human Follicle Stimulating Hormone Beta – HRP

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Pricing & Details

Product No.H101
Clone
181
Protein
Follicle Stimulating Hormone Beta
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
Mouse
IgG
Applications
ELISA Det
Prod No.
Size
Price
Avail.
Qty
Add to cart
H101-1.0 ml
1.0 ml
$178.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human Follicle Stimulating Hormone Beta (>98%)
Product Concentration
0.5 mg/ml
Formulation
This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Storage and Handling
Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Cross Reactivity
Paired with Leinco Prod. No. F103, Clone No. 176: FSH 100%, BhCG <1%, LH <4%, ihCG*, TSH <1% *3,000 mlU/ml hCG causes 4.5% decrease in observed FSH. At higher concentrations of hCG, observed FSH reduced to zero. Paired with Leinco Prod. No. C102, Clone No. 151: FSH 100%, BhCG <1%, ihCG **, FSH <1%, TSH <1%.** At high concentrations of hCG, observed FSH reduced to zero.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human Follicle Stimulating Hormone β (Clone 181) recognizes Human Follicle Stimulating Hormone β. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Follicle-stimulating hormone (FSH) is a heterodimeric glycoprotein and is composed of alpha and beta subunits. Alpha subunit is common to FSH and LH, while a unique beta subunit determines the biological specificity of each hormone. The synthesis of beta subunit is the primary rate-limiting step in the synthesis of each hormone.1 Human mutations in the FSH beta gene have been shown to produce complete deficiency states in which pubertal development and reproductive capacity are inhibited.2

Antigen Details

References & Citations

1. Ryu KZ et al. (2000) J Korean Soc Endocrinol. 15: 179 2. Sluss Patrick et al. (2002) J clin endocrin and metabolism 87: 3702
Indirect Elisa Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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