Anti-Human ILPIP (Intermediate Domain)

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Pricing & Details

Product No.I-489
Protein
ILPIP
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
ILP-Interacting Protein
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-489-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
I-489-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:I-496
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human ILPIP recognizes mouse, rat and human ILPIP. This polyclonal antibody was purified using affinity chromatography.
Background
ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family.1 Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1 converting enzyme of Fas-induced apotosis.1,2 This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival,3 suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

Antigen Details

Protein
PubMed

References & Citations

1. Sanna, MG. et al. (2002) J Biol Chem. 277(34):30454-62.
2. Sanna, MG. et al. (1998) Proc Natl Acad Sci U S A. 95(11):6015-20.
3. Nishigaki, K. et al. (2003) J Biol Chem. 278(15):13520-30.
IHC
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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