Anti-Human Rhodopsin – Purified

Anti-Human Rhodopsin – Purified

Product No.: R127

[product_table name="All Top" skus="R127"]

- -
- -
Clone
RET-P1
Target
Rhodopsin
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
RHO, MGC138309, MGC138311, OPN2, RP4, Visual Purple, Opsin 2
Isotype
IgG1
Applications
IHC FFPE
,
IP
,
WB

- -
- -
Select Product Size

Data

- -
- -

Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Mouse Anti-Human Rhodopsin (Clone RET-P1) recognizes a (Mr 39 kD) glycoprotein which is a visual pigment in mammals, birds, amphibians and reptiles.1,2,3
Background
Rhodopsin, also known as visual purple, is expressed in metazoan photoreceptor cells. It is a pigment of the retina that is responsible for both the formation of the photoreceptor cells and the first events in the perception of light. Rhodopsins belong to the class of G-protein coupled receptors. Rhodopsin is extremely sensitive to light, and enables night-vision. Exposed to white light, the pigment immediately bleaches, and it takes about 30 minutes to regenerate fully in humans.
Antigen Distribution
The Rhodopsin antigen is present on the photoreceptor cells in the retina. The antibody RET-P1 specifically labels the axons and synaptic pedicles of the rods being labelled.1,2,3
Research Area
Cell Biology
.
Neuroscience

References & Citations

1. Barnstable, C. J. et al. (1980) Nature 286:231 2. Hicks, D. et al. (1987) J. Histochem. Cytochem. 35:1317 3. Treisman, J. E. et al. (1988) Molec. Cell. Biol. 8:1570
IHC FFPE
Immunoprecipitation Protocol
General Western Blot Protocol

Certificate of Analysis

Formats Available

- -
- -
Prod No.
Description
R127
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.