Anti-Human Thyroid Stimulating Hormone Alpha – HRP

Anti-Human Thyroid Stimulating Hormone Alpha – HRP

Product No.: H107

[product_table name="All Top" skus="H107"]

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Clone
176
Target
Thyroid Stimulating Hormone Alpha
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
HCG, GPHa, GPHA1, CGA, Thyrotropin
Isotype
IgG
Applications
ELISA Det

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human TSH-α (>98%)
Product Concentration
0.5 mg/ml
Formulation
This horseradish peroxidase conjugate is supplied in a specially formulated stabilization diluent.(Leinco Prod. No.: S509)
Storage and Handling
Stable for at least one year when stored at 2°C - 8°C. Do not freeze.
Cross Reactivity
Paired with Leinco Prod. No. T100, Clone No. 154: TSH 100%, BhCG < 1%, ihCG***%, LH < 1%, FSH < 1%. Paired with Leinco Prod. No. T114, Clone No. 155: TSH 100%, BhCG < 1%, ihCG***%, LH < 1%, FSH < 1%. *** inhibition of reaction
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human Thyroid Stimulating Hormone Alpha (TSH-α) (Clone 176) recognizes Human Thyroid Stimulating Hormone Alpha. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3

Antigen Details

Research Area
Hormones
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IVD Raw Material

References & Citations

1. (1998) Bowen A 2. McPherson et al. (2000) Placenta 24: 941 3. Wenger, R H et al. (2003) Wildmann's Clinical Interpretation of Laboratory Tests
ELISA Det

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.