Anti-Human XIAP (CT)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen PN:X106 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2832190 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Anti-Human XIAP recognizes an epitope near the C-terminus of Human and Mouse XIAP. This polyclonal antibody was purified using affinity chromatography. Background X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of a novel family of Inhibitor of Apoptosis (IAP) proteins.1 XIAP is the best characterized and the most potent direct endogenous caspase inhibitor and is considered a key actor in the control of apoptotic threshold in cancer cells.2 XIAP may be considered as a new independent prognostic marker for early recurrence of non-muscular invasive bladder cancer.3 Antigen DetailsPubMed References & Citations1. Chow, T. et al. (2000) Oncogene 19: 4174 2. Barillé-Nion, S. et al. (2009) Haematologica 94: 87 3. Na, Y. et al. (2007) Chinese Medical Journal 120: 469 Technical ProtocolsIHC FFPE  |
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