Anti-Human XIAP (CT)

PN:X106

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

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Rabbit Anti-Human XIAP recognizes an epitope near the C-terminus of Human and Mouse XIAP. This polyclonal antibody was purified using affinity chromatography.

X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of a novel family of Inhibitor of Apoptosis (IAP) proteins.¹ XIAP is the best characterized and the most potent direct endogenous caspase inhibitor and is considered a key actor in the control of apoptotic threshold in cancer cells.² XIAP may be considered as a new independent prognostic marker for early recurrence of non-muscular invasive bladder cancer.³

1. Chow, T. et al. (2000) Oncogene 19: 4174
2. Barillé-Nion, S. et al. (2009) Haematologica 94: 87
3. Na, Y. et al. (2007) Chinese Medical Journal 120: 469