Anti-Human XIAP (CT)

Anti-Human XIAP (CT)

Product No.: X105

[product_table name="All Top" skus="X105"]

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Target
XIAP
Product Type
Polyclonal Antibody
Alternate Names
X-Chromosome Linked Inhibitor of Apoptosis, BIRC4, API3, ILP1, MIHA, XLP2
Applications
IHC FFPE
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:X106
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human XIAP recognizes an epitope near the C-terminus of Human and Mouse XIAP. This polyclonal antibody was purified using affinity chromatography.
Background
X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of a novel family of Inhibitor of Apoptosis (IAP) proteins.1 XIAP is the best characterized and the most potent direct endogenous caspase inhibitor and is considered a key actor in the control of apoptotic threshold in cancer cells.2 XIAP may be considered as a new independent prognostic marker for early recurrence of non-muscular invasive bladder cancer.3

Antigen Details

PubMed

References & Citations

1. Chow, T. et al. (2000) Oncogene 19: 4174
2. Barillé-Nion, S. et al. (2009) Haematologica 94: 87
3. Na, Y. et al. (2007) Chinese Medical Journal 120: 469
IHC FFPE
General Western Blot Protocol

Certificate of Analysis

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Prod No.
Description
X105
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.