Anti-Ketamine – (Clone KET-0498)

Anti-Ketamine – (Clone KET-0498)

Product No.: K200

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Clone
KET-0498
Target
Ketamine
Formats AvailableView All
Product Type
Hybridoma Monoclonal Antibody
Isotype
Mouse IgG2a k
Applications
ELISA
,
Lateral Flow

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Select Product Size
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Antibody Details

Product Details

Host Species
Mouse
Immunogen
Ketamine-BSA
Product Concentration
≥1.0 mg/ml
Purity
>90% for SDS PAGE
Formulation
Formulated in 0.015M potassium phosphate buffered saline (0.85%), pH 7.2 and contains 0.05% sodium azide.
State of Matter
Liquid
Product Preparation
This monoclonal antibody is purified by ion exchange chromatography.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
2 – 8° C Wet Ice
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Anti-Ketamine (clone KET-0498) is specific for ketamine. Ketamine - 100% Norketamine - 60%
Background
Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in general anesthesia both alone and in combination with other medications. Ketamine's primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA) receptors in the brain, leading to dissociation of sensory perceptions and producing analgesic and hallucinogenic effects. Recent research has shown long-lasting antidepressant activity and chronic pain relief likely due to structural brain changes induced by the drug. Ketamine has emerged as a novel and promising treatment for certain psychiatric conditions, such as treatment-resistant depression and post-traumatic stress disorder (PTSD), administered in controlled clinical settings. However, its misuse, particularly in recreational settings, raises concerns due to its dissociative effects and potential for addiction.

Antigen Details

Research Area
Drug of Abuse
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Matched Pair
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IVD Raw Material

References & Citations

Rosenbaum SB, Gupta V, Patel P, et al. Ketamine. Treasure Island (FL): StatPearls Publishing; 2024 Jan. Link Text
Indirect Elisa Protocol
Lateral Flow

Formats Available

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Prod No.
Description
K200
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.