Anti-Ketamine – (Clone KET-0498)
Anti-Ketamine – (Clone KET-0498)
Product No.: K200
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Clone KET-0498 Target Ketamine Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Isotype Mouse IgG2a k Applications ELISA , Lateral Flow |
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Antibody DetailsProduct DetailsHost Species Mouse Immunogen Ketamine-BSA Product Concentration ≥1.0 mg/ml Purity >90% for SDS PAGE Formulation Formulated in 0.015M potassium phosphate buffered saline (0.85%), pH 7.2 and contains 0.05% sodium azide. State of Matter Liquid Product Preparation This monoclonal antibody is purified by ion exchange chromatography. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2 – 8° C Wet Ice Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Ketamine (clone KET-0498) is specific for ketamine.
Ketamine - 100%
Norketamine - 60% Background Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in
general anesthesia both alone and in combination with other medications. Ketamine's
primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA)
receptors in the brain, leading to dissociation of sensory perceptions and producing
analgesic and hallucinogenic effects. Recent research has shown long-lasting
antidepressant activity and chronic pain relief likely due to structural brain changes
induced by the drug. Ketamine has emerged as a novel and promising treatment for
certain psychiatric conditions, such as treatment-resistant depression and
post-traumatic stress disorder (PTSD), administered in controlled clinical settings.
However, its misuse, particularly in recreational settings, raises concerns due to its
dissociative effects and potential for addiction. Antigen DetailsResearch Area Drug of Abuse . Matched Pair . IVD Raw Material References & CitationsRosenbaum SB, Gupta V, Patel P, et al. Ketamine. Treasure Island (FL): StatPearls
Publishing; 2024 Jan. Link Text Technical Protocols |
Formats Available
